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Indian J Chest Dis Allied Sci ; 1990 Oct-Dec; 32(4): 209-14
Article in English | IMSEAR | ID: sea-30293

ABSTRACT

The role of two calcium channel blockers, nifedipine and verapamil was investigated in patients of bronchial asthma. Both the drugs given orally produced an insignificant rise in PEFR, FEF25-75% and FEV1. Given along with terbutaline, however, these drugs produced significantly greater increase in PEFR, FEF25-75% and FEV1 as compared to patients receiving terbutaline alone. The two calcium channel blockers also inhibited the terbutaline induced tremors and palpitation.


Subject(s)
Adult , Asthma/drug therapy , Calcium Channel Blockers/administration & dosage , Drug Interactions , Drug Therapy, Combination , Female , Humans , Male , Nifedipine/administration & dosage , Respiratory Mechanics/drug effects , Terbutaline/administration & dosage , Verapamil/administration & dosage
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